It has helped reduce the stigma associated with erectile dysfunction, providing men a means to discuss and manage this condition more openly. The introduction and success of viagra manufacturer have also had significant social and cultural impacts. However, it has also faced criticism and concerns over recreational use and its portrayal in media and advertising, which sometimes promotes unrealistic expectations about sexual performance.

Despite its benefits, viagra qiymeti Viagra is not suitable for everyone. Before starting treatment, it's essential for individuals to consult with a healthcare provider to ensure Viagra is a safe option based on their health status and other medications they may be taking. It is contraindicated in individuals who take nitrates for heart disease, as mentioned, and those with certain health conditions such as severe liver impairment or recent history of stroke or heart attack.

Additionally, it should be used cautiously in individuals with cardiovascular risk factors. Viagra's interaction with other medications, particularly those containing nitrates used in heart disease treatment, can lead to dangerous drops in blood pressure. Since its accidental discovery and subsequent release by Pfizer in 1998, Viagra has become one of the most well-known and frequently prescribed drugs in the world for enhancing sexual function. Viagra, chemically known as sildenafil citrate, is a medication primarily used to treat erectile dysfunction (ED) in men.

Normally, PDE5 breaks down a substance known as cyclic guanosine monophosphate (cGMP), which is crucial for the relaxation of smooth muscle tissue. The primary mechanism through which Viagra operates is by inhibiting an enzyme called phosphodiesterase-5 (PDE5). By blocking PDE5, Viagra essentially increases the availability of cGMP, thereby enhancing the ability to achieve and maintain an erection. cGMP facilitates blood flow, and its increased levels result in better engorgement and function of the penis during sexual arousal.

The introduction of Viagra also had significant social and cultural impacts. Moreover, it has been a catalyst for the pharmaceutical industry to invest in further research into sexual health, leading to the development of other similar medications such as Cialis (tadalafil) and Levitra (vardenafil). It brought the topic of erectile dysfunction out of the shadows and into open discussion. Viagra is typically taken orally, in the form of a pill, approximately 30 minutes to an hour before sexual activity.

Its effects can last for up to four hours, providing ample time for satisfactory sexual intercourse. The recommended starting dose is 50 mg, but this can be adjusted based on efficacy and tolerability. It's crucial for users to follow medical advice strictly and avoid exceeding the prescribed dosage to prevent adverse effects. More serious but rare side effects can include priapism (a prolonged and painful erection) and cardiovascular events such as heart attack or stroke, particularly in those with pre-existing heart conditions.

Common adverse effects include headaches, flushing, indigestion, nasal congestion, and impaired vision. While Viagra has been a game-changer in sexual health, it is not without potential side effects.